Director, Program Management I & I Full Life Cycle

Overview

The Associate Director of Program Management will serve as a strategic and operational leader for priority immunology and inflammation programs, driving assets from mid- to late-stage development through regulatory submission. This role is designed for a hands-on, agile leader who thrives in a fast-paced biotechnology environment and can rapidly translate evolving science into executable development strategy.

As a core member of the Program Team, the Director will partner closely with Clinical, Regulatory, CMC, Nonclinical, Biomarkers, Translational Sciences, and Commercial leaders to integrate strategy and execution across the full development lifecycle. This individual will ensure alignment to the Target Product Profile (TPP) and Integrated Development Plan (IDP), while enabling flexibility as data emerge and scientific understanding evolves.

Success in this role requires deep familiarity with immunology and inflammation drug development, comfort operating amid uncertainty, and the ability to balance scientific rigor with speed, capital efficiency, and enterprise priorities.

Responsibilities

• Serve as a strategic and operational lead for one or more immunology/inflammation programs, ensuring alignment between clinical strategy, translational insights, and regulatory pathways.

• Develop and maintain integrated, cross-functional development plans across clinical, regulatory, CMC, manufacturing, and translational functions.

• Lead scenario planning exercises to evaluate alternative development pathways, indication sequencing, acceleration opportunities, and capital-efficient trade-offs.

• Continuously pressure-test timelines and critical paths, proactively identifying opportunities to streamline execution without compromising quality.

• Establish proactive risk identification and mitigation frameworks tailored to immunology/inflammation programs, including biomarker risk, patient heterogeneity, regulatory complexity, and competitive landscape shifts.

• Lead high-quality risk discussions at the Global Program Team level with timely escalation of high-impact issues.

• Develop contingency strategies for clinical, manufacturing, or regulatory inflection points.

• Monitor program-level budget and resource health in alignment with corporate priorities.

• Ensure clarity of functional accountabilities and decision rights in a lean, matrixed biotech structure.

• Partner with functional leaders during long-range planning and portfolio prioritization exercises.

• Build and maintain practical, real-time tracking tools (e.g., Smartsheet dashboards, integrated timelines, risk logs) that enable rapid visibility and decision-making.