Engineering Manager - Blood Platform

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.Position Summary

Caris Life Sciences is one of the largest precision-oncology platforms in the world, serving hundreds of thousands of molecular cases a year and growing at double-digit rates. Behind every case is a matched molecular, imaging, and clinical-outcomes data estate few organizations anywhere can rival, and the clinical software that drives the lab's instruments and processes, captures results, and delivers each patient's report. A patient and an ordering physician are waiting on every one of those reports. The Engineering Manager leads one of the front-line teams that keep that software reliable and moving.

This assignment leads the blood-platform engineering team, spanning the laboratory information systems behind Caris Assure and Caris Detect blood operations. The team is growing with the blood product roadmap and pairs closely with its Product Manager counterpart.

The Engineering Manager - Clinical Software Products leads a front-line engineering team in Caris Life Sciences' Clinical Software Engineering organization, reporting to the Senior Director, Clinical Software Engineering. This is a player-coach position: the Engineering Manager owns delivery, quality, and operational health for an assigned platform team while staying technically engaged in design and code review. The platforms in scope are live, business-critical clinical systems under SOX financial controls and FDA regulatory requirements, and the Engineering Manager is directly accountable for the supervision, change-control discipline, and engineering standards those obligations demand.

The engineering environment is modern and funded: frontier AI coding assistants are standard-issue tooling, with agentic workflows across design, implementation, and test generation. Characterization tests and golden-master replay validation serve as executable evidence for regulated change. Delivery runs on CI/CD with application-level observability and risk-based release governance aligned with current FDA Computer Software Assurance guidance. Modernization of established systems is active, funded engineering work. The Engineering Manager runs the team on this model and is accountable for making automation-first practice its daily norm.