Senior AI and Large Language Model (LLM) Engineer
Senior AI/LLM engineer serving as subject matter expert for a consulting team supporting NCBI (NIH) in Bethesda, MD, on-site. Day to day: designing, fine-tuning, and deploying LLMs and RAG pipelines for biomedical search and knowledge discovery, guiding architecture across product teams. Core stack: Python, PyTorch, Hugging Face, embeddings and vector databases.
- Compensation
- Not disclosed
- Location
- NIH-Bethesda
- Work setup
- Not specified
- Seniority
- Senior
- Employment
- Not specified
- Experience
- 1+ years
- Category
- Ai engineering
- Posted
Skills
Must have
- 3+ years of hands-on experience with large language models (training, fine-tuning, augmentation, or deployment)
- At least 3+ years of experience after last degree; recent master's graduates not sought
- Experience integrating LLMs into production systems (semantic search, RAG pipelines, domain-specific QA)
- Strong experience in ML system architecture and scalable deployment
- Proven ability to work cross-functionally with product and technical teams
- Experience serving as a technical SME guiding multi-team initiatives
- Strong programming skills in Python
- Experience with modern ML frameworks (PyTorch, Hugging Face) and retrieval infrastructure (embeddings, vector databases)
Nice to have
- Experience building LLM-based systems for biomedical research or life sciences
- Familiarity with large scientific corpora, biomedical ontologies, structured knowledge bases, or biological datasets
- Experience developing generative AI systems for DNA, RNA, or protein sequence analysis
- Background in bioinformatics, computational biology, or related disciplines
- Experience improving factual grounding and reducing hallucinations in scientific or regulated environments
Full description
LOCATION: Bethesda, Maryland (On-site / Not-remote)Overview
We are seeking an experienced AI/LLM Engineer to lead the design, customization, and integration of large language models (LLMs) into biomedical research workflows and information retrieval systems. We are looking for someone with hands-on experience training, fine-tuning, augmenting, and deploying LLMs in production environments, ideally within biomedical or life sciences domains. The role is product-oriented and forward-looking, focused on building the next generation of AI-enabled search, retrieval, and knowledge discovery tools.
This role serves as a subject matter expert (SME) across multiple product and engineering teams. The selected candidate will help define, architect, and implement LLM-driven capabilities across a portfolio of NCBI services. The position requires strong technical depth, sound architectural judgment, and the ability to collaborate effectively within existing product and technical ecosystems.
This is a hands-on, build-oriented role with strategic influence. The candidate must be capable of guiding both what gets built and how it gets built.
Only serious candidates accepted - we are not seeking candidates that have recently graduated with a masters degree in the past 1-2 years.
We are seeking candidates with at least 3+ years experience doing this work after your last degree.
Key Responsibilities
- Serve as the AI/LLM subject matter expert across product and engineering teams.
- Collaborate with product managers and technical leads to define AI-enabled capabilities and define the use of LLMs across NCBI platforms (e.g., PubMed and related systems).
- Develop and implement retrieval-augmented generation (RAG) systems integrating LLMs with large-scale biomedical datasets.
- Provide architectural guidance on model selection, domain adaptation, evaluation strategies, and deployment approaches.
- Improve model grounding, factual accuracy, and scientific reliability in domain-sensitive applications.
- Support engineering teams in productionizing AI solutions, ensuring scalability, performance, and maintainability.
- Evaluate emerging LLM techniques and recommend practical adoption strategies aligned with organizational priorities.
Required Qualifications
- 3+ years of hands-on experience working with large language models (training, fine-tuning, augmentation, or deployment).
- Demonstrated experience integrating LLMs into production systems (e.g., semantic search, RAG pipelines, domain-specific QA).
- Strong experience in ML system architecture and scalable deployment.