Senior Clinical Research Associate
- Compensation
- Not disclosed
- Location
- San Diego, California, United States
- Work setup
- Not specified
- Seniority
- Senior
- Employment
- Not specified
- Experience
- 3+ years
- Category
- Healthcare
- Posted
Skills
Must have
- 5 years in clinical research and development
- 3 years onsite monitoring/site management experience
- Experience managing/supervising vendors
- Highly proficient knowledge and understanding of ICH-GCP
Nice to have
- 4-year college degree
- CRA certification
- Strong organizational skills and attention to detail
- Excellent site management and monitoring skills
- Proficient software skills (Outlook, Word, Excel, Power Point, MS Project)
- Proficient in Veeva eTMF and Medidata EDC
- Ability to perform key duties in a timely manner and with minimal supervision
- Ability to think critically (analyze, extrapolate knowledge and information and problem-solve)
- Ability to work effectively independently and in a collaborative team environment
- Must be able to work collaboratively and professionally with team members and outside vendors such as CROs
- Excellent interpersonal, verbal and written communication skills
- Ability to multi-task and prioritize appropriately
- Displays high level of professionalism and understands need for confidentiality in all aspects of position
Full description
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Sr. Clinical Research Associate (Sr. CRA) provides support to Study Lead(s) in clinical study planning, execution and management. The primary purpose of the position is to support the COM/Study Lead in study set-up, execution, oversight, and closeout activities in compliance with the clinical protocol, regulatory requirements, ICH GCP guidelines and governing policies & procedures.
Responsibilities
- Support assigned study teams with TMF set-up, maintenance, ongoing quality control reviews, and final reconciliation of study documents
- Routinely monitor TMF inspection readiness for assigned studies
- Assist Study Lead in review of invoices for assigned studies
- Contribute to development and finalization of Pharmacy Manual and associated forms, templates and processes
- Assist study lead with investigational product and ancillary supplies management, accountability and reconciliation activities
- Support IRT system set-up, testing, and on time activation including review of specifications, and user manuals.
- Collect and/or review Essential Documents from investigational sites